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THC is the main psychoactive compound in cannabis and is responsible for the familiar high or stoned feeling. In this article, you'll learn what THC is, how it affects your body, how long its effects can last and what risks are associated with its use.
THC stands for tetrahydrocannabinol. It is a cannabinoid, one of the compounds that occur naturally in the cannabis plant. Cannabinoids are found in particularly high concentrations in the flowers, which are commonly used as cannabis or processed into hash.
What sets THC apart from many other cannabinoids is its psychoactive effect. It can cause feelings of relaxation or euphoria, but may also change your perception of time, make it harder to concentrate and slow down your reaction time.
THCa is the natural precursor to THC. Fresh cannabis contains a significant amount of THCa, which does not produce the typical psychoactive effects associated with THC. When heated, THCa is partially converted into THC. This process is known as decarboxylation and occurs when cannabis is smoked, vaporised or heated during cooking.
THC interacts with the endocannabinoid system, a natural system in the body involved in processes such as mood, appetite, memory, sleep and pain perception.
This system contains several types of cannabinoid receptors. THC primarily binds to CB1 receptors, which are especially common in the brain and nervous system. This temporarily changes the way certain signals are processed in the brain.

THC can produce both pleasant and unpleasant effects. How someone responds depends on factors such as the dose, previous experience, individual sensitivity and the setting in which cannabis is used.
Common effects include:
A higher dose does not automatically mean a more enjoyable experience. Too much THC can instead cause dizziness, nausea, anxiety, panic, paranoia or confusion. An unpleasant experience like this is often referred to as a bad trip.
When cannabis is smoked or vaped, the effects are usually noticeable within a few minutes. They tend to be strongest during the first few hours before gradually wearing off.
Edibles, such as space cake or gummies, work differently. The THC first has to pass through the digestive system and liver, which means it can take around 30 to 90 minutes before the effects become noticeable. In the liver, THC is converted into compounds including 11-hydroxy-THC.
As a result, the effects of edible cannabis can last considerably longer. While smoked or vaporised cannabis is usually noticeable for several hours, the effects of edibles can last for up to around 12 hours.
This delayed onset can also make edibles more difficult to dose. Taking more because you do not feel anything yet can result in consuming much more THC than intended and lead to an unpleasant experience.
THC is mainly found in cannabis flower and hash, but it may also be present in edibles, cannabis oils and vape products. The way THC is consumed has a major influence on how quickly the effects begin and how long they last.

THC is psychoactive, while CBD is not. Both cannabinoids occur naturally in cannabis, but they interact with the body in different ways.
THC interacts strongly with CB1 receptors in the brain and can therefore alter awareness and perception. CBD, short for cannabidiol, does not produce the same psychoactive cannabis high.

THC side effects can occur during or shortly after use. Their intensity varies from person to person and depends on factors such as the dose and individual sensitivity.
Common side effects include:
At higher doses, or in people who are particularly sensitive, cannabis can also trigger or worsen more serious psychological symptoms.
The risks associated with cannabis use depend largely on how much and how often someone uses it, the age at which they start, the method of consumption and their individual sensitivity.
Important risks include:
The method of consumption also makes a difference. With edibles, for example, it can be easier to unintentionally consume too much because the effects take longer to begin.
Cannabis containing THC can be addictive, although not everyone who uses cannabis develops a dependence. The risk increases with frequent use, starting at a young age and long-term daily or near-daily use.
Regular use can also lead to tolerance. This means the body becomes accustomed to the effects, so a larger amount of cannabis may be needed to achieve the same effect.
Signs of problematic use can include:
People who use cannabis heavily and regularly may experience withdrawal symptoms when they stop or significantly reduce their use. This does not happen to everyone, and the severity of the symptoms varies from person to person.
Possible symptoms include:
Most symptoms gradually become less intense. They often improve noticeably within one to two weeks, although sleep problems can sometimes last longer.
The psychoactive effects of THC usually last for several hours, but its metabolites can remain detectable in the body for much longer.
Exactly how long varies from person to person and depends on factors including:
With regular use, THC metabolites can remain detectable for longer than after occasional use. A positive test therefore does not automatically mean that someone is still high at that moment.
There is no reliable quick method for immediately removing THC from the body.
Yes. It is possible to consume more THC than feels comfortable. This can happen relatively easily with edibles because their effects take longer to begin, which may lead someone to take another dose too soon.
Too much THC can cause symptoms such as anxiety, panic, nausea, dizziness, paranoia and confusion. If this happens, avoid taking any more cannabis and allow the effects to gradually wear off.
Do not consume any more cannabis and move to a calm, familiar environment. An overly intense high can feel unpleasant, but in most cases the effects will gradually pass on their own.
It may help to:
Various methods are suggested online for quickly stopping a cannabis high, including CBD, mango and black pepper. However, there is not enough evidence to show that these methods reliably neutralise the effects of THC.
If you experience severe symptoms, problems with consciousness, chest pain or anything else that causes serious concern, seek medical assistance.
No. THC can affect reaction time, concentration and coordination, which can increase the risk of an accident.
Even if you no longer feel high, your attention and reaction time may still be affected. Avoid driving while you are still experiencing any effects of cannabis.
Noah van Knippenberg
Content Specialist Novus Fumus
Noah van Knippenberg writes for Novus Fumus about cultivation techniques, mushrooms, and smartshop-related topics. Drawing from his practical experience, he translates complex subjects into accessible and reliable information.
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